Measles-compatible illness and laboratory confirmation of infection in the absence of recent (i.e. within the previous 28 days) immunization with measles-containing vaccine.
Laboratory confirmation may be determined by:
- Isolation of measles virus from an appropriate clinical specimen
OR
- Detection of measles virus RNA OR
- Significant rise in measles IgG titre between acute and convalescent sera
OR
- Positive serologic test for measles IgM antibody using a recommended assay in a person who is either epidemiologically linked to a laboratory-confirmed case or has recently travelled to an area of known measles activity
OR
Clinical illness in a person who is epidemiologically linked to a laboratory-confirmed case
Clinical illness in the absence of appropriate laboratory tests and not epidemiologically linked to a laboratory-confirmed case and with recent travel to an area of known measles activity.
All of the following:
- Fever of 38.3° C or greater
- Cough, coryza or conjunctivitis
- Generalized maculopapular rash of any duration
Clinical illness is characterized by all of the following features:
- Fever of 38.3° C or greater
- Cough, coryza or conjunctivitis
- Generalized maculopapular rash for at least 3 days
