- Laboratory confirmation of infection by:
- Isolation of Bordetella pertussis from an appropriate clinical specimen [2];
OR - Detection of B. pertussis DNA [3] from an appropriate clinical specimen and one or more of the following:
- Cough lasting 2 weeks or longer;
OR - Paroxysmal cough of any duration;
OR - Cough with inspiratory "whoop";
OR - Cough ending in vomiting or gagging, or associated with apnea.
- Epidemiological link to a laboratory-confirmed case and one or more of the following for which there is no other known cause:
- Paroxysmal cough of any duration;
OR - Cough with inspiratory "whoop";
OR - Cough ending in vomiting or gagging, or associated with apnea.
- Cough lasting 2 weeks or longer in the absence of appropriate laboratory tests and not epidemiologically linked to a laboratory-confirmed case;
AND - One or more of the following with no other known cause:
- Paroxysmal cough of any duration;
OR - Cough with inspiratory "whoop";
OR - Cough ending in vomiting or gagging, or associated with apnea.
- One or more of the following with no other known cause:
- Paroxysmal cough of any duration;
- OR
- Cough with inspiratory "whoop";
OR - Cough ending in vomiting or gagging, or associated with apnea.
Notes- Pertussis is also called "whooping cough".
- Nasopharyngeal swab or nasopharyngeal wash.
- Pertussis DNA is detectable using a polymerase chain reaction (PCR) assay.
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